Though 90–200 mg of CoQ10 per day is typically recommended, needs can vary depending on the person and condition being treated ( 8). Various factors can deplete CoQ10 levels, which is why supplements may become necessary.ĭosage Recommendations by Health Condition SummaryĬoQ10 is a compound with many important functions in your body. Supplementing with CoQ10 has been shown to counteract damage or improve conditions related to a deficiency in this important compound.Īdditionally, as it’s involved in energy production, CoQ10 supplements have been shown to boost athletic performance and decrease inflammation in healthy people who are not necessarily deficient ( 7). Other causes of CoQ10 depletion include statin medication use, heart disease, nutrient deficiencies, genetic mutations, oxidative stress and cancer ( 6). For example, the rate of its production significantly declines with age, which is associated with the onset of age-related conditions like heart disease and cognitive decline ( 5). Though your body makes CoQ10, several factors can deplete its levels. Ubiquinone is converted to its active form, ubiquinol, which is then readily absorbed and utilized by your body ( 2).Īside from being naturally produced by your body, CoQ10 can be obtained through foods including eggs, fatty fish, organ meats, nuts and poultry ( 3).ĬoQ10 plays a fundamental role in energy production and acts as a powerful antioxidant, inhibiting free radical generation and preventing cell damage ( 4).
There are two different forms of CoQ10 in your body: ubiquinone and ubiquinol. Mitochondria - often referred to as the powerhouses of cells - are specialized structures that produce adenosine triphosphate (ATP), which is the main source of energy used by your cells ( 1). Coenzyme Q10, or CoQ10, is a fat-soluble antioxidant present in all human cells, with the highest concentration in the mitochondria.
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